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BCH 471 Medical Biochemistry I
Biochemistry of biologically important compounds and molecular biology for medical students. DNA, RNA, structure, replication, transcription, translation, protein structure, protein modifications, hemoglobin, immunoglobin, sickle cell anemia, fibrillar proteins, enzymology and kinetics, enzyme regulation, blood clotting, membranes, membrane proteins, hormones, gene regulation, recombinant DNA, cystic fibrosis, transgenic animals, oncogenes, chemotherapeutic agents, small group clinical case studies on hepatitis, fragile X, DNA repair and pertussis. Multiple choice tests. WI [5]
BCH 472 Medical Biochemistry II
Biochemistry of intermediary metabolism and nutrition for medical students. Bioenergetics, redox reactions, Krebs cycle, carbohydrate metabolism, glycolysis, gluconeogenesis, pentose phosphate pathway, glycoproteins, osteoarthritis, lipid metabolism, synthesis and degradation, special lipids, cholesterol, coronary heart disease, amino acid metabolism, urea cycle, bioactive amino acid products, glutathione, amino acid disorders, nucleotide metabolism and disorders, biotransformations, nutrition, small group clinical case studies pancreatic insufficiency, Gaucher disease, diabetes, urea cycle disorders. Multiple choice tests. SP [5]
BCH 505 Advanced Biochemistry
Continuation of BCH 471, and 472 at the graduate level. Special emphasis is given to protein biochemistry, enzymology and molecular biology. SP [4]
BCH 571, 572 Medical Biochemistry I, II
Medical Biochemistry for graduate students. Graduate students take same lecture classes as medical students (BCH 471, 472). Instead of classes devoted to clinical studies or case studies in small group discussions, the graduate students receive supplemental lectures focused on experimental techniques, experimental design and biochemical calculations, pH and buffers, bioenergetics and redox chemistry, proteomics, carbohydrate chemistry, lipids, hormone receptors, signaling, and protein turnover. Essay examinations. WI and SP [5] [5]
BCH 581 Biochemical Research Techniques
Graduate students complete a laboratory rotation in one faculty member's laboratory for the whole quarter. They learn several research techniques, experimental design, data collection and analysis. Research projects are related to ongoing efforts in the laboratory. Students complete a written laboratory report at the end of the quarter and also give an oral presentation of their work. FA [4]
BCH 582 Biochemical Methodology
Graduate students complete a second laboratory rotation in a different laboratory. This laboratory experience is meant to complement the first quarter rotation and learn a new set of research techniques. WI [4]
BCH 585 Extramural Research
An eight to ten week [usually spring quarter] experience at an industrial research laboratory in Europe or the United States. Student will focus on major and minor research areas. Assigned reading, a final examination and a written report are required. SP [5]
BCH 595 Journal Club
Discussion and presentation of both historical and current journal articles. Often the articles are chosen to correspond to the topics being covered in the other biochemistry classes. WI, SP [1-2]
BCH 598 Biochemistry Master's Research
Biochemistry thesis research for master's students. [v]
BCH 624 Connective Tissue Biochemistry
Biochemistry of the extracellular matrix in connective tissues. Topics include collagen genes, structure, types, biosynthesis and diseases; proteoglycan structure, synthesis and diseases, hyaluronan; calcification of connective tissues, bone morphogenic proteins, basement membranes, elastin, fibronectin, extracellular matrix receptors, matrix metalloproteinases, and matrix metalloproteinase gene regulation. SP [3]
BCH 690 Minicourses
[1]
BCH 698 Introduction to Research
Each faculty member in the department of biochemistry discusses the research performed in their laboratory with the first year graduate students. FA [2]
BCH 699 Biochemistry Doctoral Research
Biochemistry dissertation research for doctoral students. [v]
BCH 900 Independent Study
[v]
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